Jobi McAnuff will make his first start for Leyton Orient this evening at Plymouth in the Capital One Cup first round.
McAnuff starts on the wing for the O's while there are full debuts for goalkeeper Gary Woods and striker Jay Simpson.
There is no place for Saturday's goalscorer Darius Henderson and it is understood the striker has not travelled to Plymouth.
Leyton Orient: Woods; Omozusi, Clarke, Baudry, Sawyer; Batt, Bartley, James, McAnuff; Mooney, Simpson
Subs: Legzdins, Vincelot, Cuthbert, Cox, Lisbie, Lowry, Pritchard