A teenager collapsed and died in Chingford, earlier this week.
Police and paramedics were called to an address in Connington Crescent at around 7pm on Wednesday.
Emergency services rushed the girl to hospital in an ambulance but she was later pronounced dead.
Next of kin are aware.
A post mortem examination on Friday proved inconclusive and officers are awaiting toxicology reports.
A spokesman said: “Whist at this early stage there is nothing to suggest the death is suspicious, it is being treated as unexplained pending additional post mortem tests.
“Enquiries into the circumstances of the death are being carried out by officers from Waltham Forest Borough.”
A neighbour said they saw a number of young girls crying as the paramedics arrived.
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