Southminster St Leonards took a huge step towards securing the Premier Division title after an emphatic 3-1 win over title rivals Frenford Senior on Saturday.
Frenford - Olympian League champions for the past two seasons - went ahead through Brad Foley before Greig Taylor equalised for Southminster.
Josh McEvoy put Southminster in the lead and Ross Adams sealed the victory from 25 yards out, ensuring Southminster only need a point against Buckhurst Hill to guarantee the league title on Wednesday evening.
Frenford Senior will have to wait until Saturday to host Manford Way, but they can no longer overhaul Southminster.
Kelvedon Hatch could only earn a 3-3 draw against relegation battlers White Ensign, all but ending their hopes of landing the title.
Lee Cody, Mike Daniels and Bill Munroe were all on target for Kelvedon, but goals from Bill Crumpton, Lee Delf and Jamie Brown gave White Ensign a crucial point.
Fourth-place Kelvedon still hold five games in hand on the rest of the division, but will need to win them all to snatch the title from Southminster's grasp.
They travel to Wadham Lodge on Wednesday.
White Ensign are now just a point behind Harold Wood ahead of their relegation clash on Wednesday.
A Ricky Bailey strike earned Manford Way a hugely important 1-0 victory over Wadham Lodge in their fight against relegation.
Manford are now four points clear of the drop with two to play.
Harold Hill gained just their second win of the season securing a 4-3 victory against May & Baker E.C.
Ricky Reid and Martin Begg both bagged a brace for the already-relegated Harold Hill.
Rayleigh Town moved up to sixth after beating Newbury Forest 4-2.
Toch Singh, Tom Prendergast, John Taylor and Neil Harris scored for Rayleigh Town, cancelling out Luke Wilson’s brace. Hannakins Farm are the visitors to Rayleigh on Wednesday.
Newham United secured the Division One title with an emphatic 6-1 victory over Old Southendian on Saturday.
Lee Springer scored a brace, while Alf Dickenson, Hamzy Tomanday, John Offei and Bradley Thomas completed the rout to win the league in style.
Newham finished two points ahead of the chasing pack, with Springfield gaining promotion on goal difference.
Runwell Hospital ended their campaign with an impressive 6-0 thrashing of Basildon Town on Saturday.
Adam Green netted a hat trick, while Jeff Banks came off the bench to score a brace with Aaron Rixon completing the scoring to secure fourth place for the home side.
Anagrams Records Trophy Final
Galleywood bowed out of the Anagrams Records Trophy after losing 3-0 to an in-form Kent Athletic in the final.
The Spartan South Midlands side proved too strong for Galleywood, who finished the match with ten men following the dismissal of Jack Bond.