Emmanuel Adebayor is back in training and could start for Tottenham's Europa League trip to Panathinaikos.
The Togolese striker has recovered from a hamstring injury and has yet to feature for Spurs since signing a permanent deal in the summer.
Benoit Assou-Ekotto, Scott Parker and Younes Kaboul are all still unavailable while Kyle Naughton is a doubt meaning Jan Vertonghen may once again fill in at left-back.
Goalkeeper Hugo Lloris is set to once again start in goal in place of Brad Friedel.
Andre Villas-Boas is likely to play a strong side, despite Spurs playing against Aston Villa three days later on Sunday.
Tottenham drew their opening home game against Lazio 0-0 and will be looking to get a win under their belts in a competition Villas-Boas views as a good opportunity to win a trophy.
Possible starting XI:- Lloris, Walker, Gallas, Caulker, Vertonghen, Sandro, Dembele, Lennon, Dempsey, Bale, Adebayor