Four people were arrested after gunfire was heard near Leyton Midland Road station.
No injuries were reported after the incident, which comes amid a spate of stabbings and shootings in Waltham Forest which have left three people dead.
A spokesman for Scotland Yard said: "Police were called at 15:00hrs on Friday, 13 April to reports of shots fired in Midland Road, E10.
"Officers, including firearms officers, attended.
"No injuries have been reported.
"Four people were arrested on suspicion of public order offences. All have been released under investigation."
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